Lulu Attack EX Premium 36 Tablets [Designated Class 2 OTC Drug]

Product Information

A cold medicine that suppresses the [inflammation] that causes unpleasant cold symptoms.
1. Contains a double combination of the anti-inflammatory ingredients ibuprofen 600 mg and tranexamic acid 750 mg (per 9 tablets). Highly effective for sore throat, fever, etc.
2. Thanks to a proprietary formulation technology, ibuprofen dissolves quickly and takes effect.
3. The antihistamine ingredient d-chlorpheniramine maleate suppresses the allergic symptoms of a cold (runny nose, nasal congestion, etc.).
4. Dihydrocodeine phosphate and dl-methylephedrine hydrochloride calm distressing coughs.
5. PTP packaging that is convenient to carry.

Deviating from the specified dosage and administration of a medicine leads to serious harm to health. Always read the product instructions carefully before use and follow the dosage and administration. Even when a medicine is used correctly according to the dosage and administration, side effects may occur. If you notice anything unusual, stop use immediately and consult a doctor or pharmacist.

●Precautions for Use
■■Things You Must Not Do■■
(Failure to follow these instructions may worsen current symptoms or increase the risk of side effects or accidents)
1. The following persons must not take this medicine.
(1) Persons who have had allergic symptoms caused by this medicine or its ingredients
(2) Persons who have experienced asthma after taking this medicine or other cold medicines or antipyretic analgesics
(3) Children under 15 years of age
(4) Pregnant women within 12 weeks of their expected delivery date
(5) Persons receiving treatment for the following diseases or being administered the following medicines at a medical institution
Gastric/duodenal ulcer, blood disease, liver disease, kidney disease, heart disease, hypertension, persons being administered zidovudine (Retrovir)
2. Do not use any of the following medicines while taking this medicine.
Other cold medicines, antipyretic analgesics, sedatives, antitussive and expectorant medicines, oral medicines containing antihistamines, etc. (oral medicines for rhinitis, motion sickness medicines, allergy medicines, etc.), oral medicines containing tranexamic acid
3. Do not drive a vehicle or operate machinery after taking this medicine.
(Symptoms such as drowsiness may occur)
4. If you are breastfeeding, do not take this medicine, or avoid breastfeeding while taking this medicine.
5. Do not drink alcohol before or after taking this medicine.
6. Do not take this medicine for more than 5 days.
■■Things To Consult On■■
1. The following persons should consult a doctor, pharmacist or registered salesclerk before taking this medicine.
(1) Persons receiving treatment from a doctor or dentist
(2) Persons who are pregnant or who think they may be pregnant
(3) Elderly persons
(4) Persons who have had allergic symptoms caused by medicines, etc.
(5) Persons with the following symptoms
High fever, difficulty urinating
(6) Persons who have received the following diagnoses
Thyroid dysfunction, diabetes, glaucoma, systemic lupus erythematosus,
Mixed connective tissue disease, bronchial asthma, persons with thrombosis (cerebral thrombosis, myocardial infarction, thrombophlebitis, etc.), persons at risk of developing thrombosis, respiratory dysfunction, obstructive sleep apnea syndrome, obesity
(7) Persons who have had the following diseases
Gastric/duodenal ulcer, ulcerative colitis, Crohn's disease, blood disease, liver disease, kidney disease
2. If any of the following symptoms appear after taking this medicine, they may be side effects. Stop taking it immediately and consult a doctor, pharmacist or registered salesclerk, bringing this document with you.

Relevant Area – Symptoms
Skin – Rash/redness, itching, bruising
Digestive system – Nausea/vomiting, loss of appetite, stomach discomfort, stomach pain, mouth ulcers, heartburn, stomach heaviness, gastrointestinal bleeding, abdominal pain, diarrhea, bloody stool
Neuropsychiatric system – Dizziness, insomnia, depressed mood
Circulatory system – Palpitations
Respiratory system – Shortness of breath
Urinary system – Difficulty urinating
Other – Blurred vision, ringing in the ears, swelling, nosebleeds, bleeding gums, bleeding that is difficult to stop, bleeding, back pain, general fatigue

The following serious symptoms may occur rarely.
In such cases, see a doctor immediately.

Symptom Name – Symptoms
Shock (anaphylaxis) – Immediately after taking this medicine, symptoms such as itching of the skin, hives, hoarseness, sneezing, itchy throat, difficulty breathing, palpitations, and clouding of consciousness may occur.

Blood disorder – Symptoms such as sore throat, fever, general fatigue, paleness of the face and the inside of the eyelids, bleeding easily (bleeding gums, nosebleeds, etc.), and bruising (that does not fade when pressed) may occur.

Digestive disorder – Symptoms such as black stool, vomiting of blood, bloody stool, and mucous bloody stool (soft stool mixed with blood, mucus and pus) may occur.

Mucocutaneous ocular syndrome (Stevens-Johnson syndrome),
Toxic epidermal necrolysis – Symptoms such as high fever, bloodshot eyes, eye discharge, lip sores, sore throat, and widespread skin rash/redness may persist or suddenly worsen.

Liver dysfunction – Symptoms such as fever, itching, rash, jaundice (yellowing of the skin and whites of the eyes), brown urine, general fatigue, and loss of appetite may occur.

Renal disorder – Symptoms such as fever, rash, decreased urine output, generalized swelling, general fatigue, joint pain (aching joints), and diarrhea may occur.

Aseptic meningitis – Symptoms such as severe headache accompanied by a stiff neck, fever, and nausea/vomiting may occur. (Such symptoms have been reported particularly often in persons receiving treatment for systemic lupus erythematosus or mixed connective tissue disease)

Myocardial infarction – Tightening chest pain, difficulty breathing, and cold sweat.

Cerebrovascular disorder – Symptoms such as reduced or lost consciousness, difficulty moving the limbs on one side, headache, vomiting, dizziness, difficulty speaking, and difficulty forming words may appear suddenly.

Interstitial pneumonia – Symptoms such as shortness of breath or difficulty breathing when climbing stairs or exerting oneself slightly, dry cough, and fever may occur. These symptoms may appear suddenly or persist.

Asthma – Symptoms such as wheezing or whistling sounds when breathing and difficulty breathing may occur.

Aplastic anemia – Symptoms such as bruising, nosebleeds, bleeding gums, fever, pale-looking skin and mucous membranes, fatigue, palpitations, shortness of breath, feeling unwell with lightheadedness, and blood in the urine may occur.

Agranulocytosis – Symptoms such as sudden high fever, chills, and sore throat may occur.

Respiratory depression – Symptoms such as shortness of breath and difficulty breathing may occur.

3. If symptoms such as an excessive drop in body temperature, prostration (lack of strength) or cold extremities (cold hands and feet) appear after taking this medicine, stop taking it immediately and consult a doctor, pharmacist or registered salesclerk, bringing this document with you.

4. The following symptoms may appear after taking this medicine. If these symptoms persist or worsen, stop taking it and consult a doctor, pharmacist or registered salesclerk, bringing this document with you.
Constipation, dry mouth, drowsiness

5. If symptoms do not improve after taking this medicine 5 to 6 times, stop taking it and consult a doctor, pharmacist or registered salesclerk, bringing this document with you.
(Especially when fever continues for 3 days or more or recurs)



●Indications
Relief of the various symptoms of a cold (sore throat, fever, chills, headache, runny nose, nasal congestion, sneezing, cough, phlegm, joint pain, muscle pain)



●Dosage and Administration
Take the following dose with water or warm water.
Age – Single Dose – Doses per Day
Adults (15 years of age or older) – 3 tablets – 3 times: take preferably within 30 minutes after meals.
Under 15 years of age – Do not take this medicine.

<Precautions Concerning Dosage and Administration>
(1) Strictly follow the dosage and administration.
(2) How to remove the tablets
Press the raised part of the PTP sheet containing the tablet firmly with your fingertip to break the aluminum foil on the back, then remove the tablet and take it. (If the sheet is accidentally swallowed as is, it may lead to unexpected accidents such as piercing the esophageal mucosa)



●Ingredients and Amounts
This medicine is a white film-coated tablet, and 9 tablets contain the following ingredients.
Ingredient – Amount – Action
Ibuprofen – 600 mg
– Acts on [prostaglandins], the source of inflammation and pain, to suppress sore throat, etc. and reduce fever.

Tranexamic acid – 750 mg
– Suppresses [plasmin], the source of inflammation, and relieves swelling and pain of the throat.

d-Chlorpheniramine maleate – 3.5 mg
– Suppresses the allergic symptoms of a cold (runny nose, nasal congestion, etc.).

dl-Methylephedrine hydrochloride – 60 mg
– Widens the bronchi and calms coughing.

Dihydrocodeine phosphate – 24 mg
– Acts on the cough center to calm coughing.

Anhydrous caffeine – 75 mg
– Relieves headache.

Benfotiamine (vitamin B1 derivative) – 25 mg
– Promotes the recovery of physical strength depleted by a cold.

Riboflavin (vitamin B2) – 12 mg
– Keeps the mucous membranes of the throat, nose, etc. healthy.

Additives: polyoxyethylene hydrogenated castor oil, hypromellose, D-mannitol, cellulose, hydroxypropylcellulose, anhydrous silicic acid, talc, croscarmellose Na, polyvinyl alcohol (partially hydrolyzed), triethyl citrate, titanium oxide, carnauba wax

<Precautions Concerning Ingredients and Amounts>
The riboflavin (vitamin B2) contained in this medicine may cause the urine to turn yellow.



●Precautions for Storage and Handling
(1) Store in a cool, dry place out of direct sunlight.
(2) Keep out of reach of children.
(3) Do not transfer to another container. (This results in misuse or a change in quality)
(4) Do not use this product after the indicated expiration date.
Also, after opening the aluminum pouch, use within 12 months.
(5) Write the date the aluminum pouch was opened in the "Date Opened" field on the box.

[Other Information Stated in the Package Insert]
What causes a cold?
A cold is an "acute inflammatory disease of the upper respiratory tract" such as the "throat" and "nose". Viruses, etc. enter the body through the throat, nose, etc. and cause an excessive inflammatory response. This inflammatory response causes respiratory symptoms such as sore throat, runny nose, cough and phlegm, as well as fever, etc.
First controlling and calming the inflammation is the key to relieving cold symptoms.
It is also important to take vitamins and get plenty of sleep when you have a cold.



●Contact Information
Direct inquiries about this product to the store where you purchased it or to the contact below.
Daiichi Sankyo Healthcare Co., Ltd. Customer Service Office
3-14-10 Nihonbashi, Chuo-ku, Tokyo 103-8234
Phone 0120-337-336
Hours 9:00–17:00 (excluding Saturdays, Sundays, and public holidays)

Manufacturer and Distributor
Daiichi Sankyo Healthcare Co., Ltd.
3-14-10 Nihonbashi, Chuo-ku, Tokyo
Website

Translation Notice

• This product is manufactured and labeled for sale and use in Japan in accordance with Japanese laws and regulations.
• This English product information is a translation of the original Japanese product information and is provided for reference only. It does not guarantee that the product or this information conforms to the laws and regulations of any country other than Japan.
• The translation may contain errors or omissions and may be revised without notice. If there is any discrepancy between this translation and the original Japanese text, the original Japanese text takes precedence. The original is available on the Japanese version of this page.