Lulu Attack EX 24 Tablets [Designated Class 2 OTC Drug]

Product Information

A combination cold medicine containing 8 ingredients that are highly effective against troublesome cold symptoms such as sore throat and fever.
1. The 2 anti-inflammatory ingredients tranexamic acid and ibuprofen suppress the inflammation that underlies troublesome cold symptoms, providing excellent relief from sore throat, fever, etc.
2. The long-acting antihistamine ingredient clemastine fumarate suppresses the allergic symptoms of a cold (runny nose and nasal congestion).
3. The expectorant ingredient bromhexine hydrochloride makes it easier to cough up phlegm, which causes coughing.
4. Dihydrocodeine phosphate and dl-methylephedrine hydrochloride calm troublesome coughs.
5. Aluminum PTP packaging that is convenient to carry.

Deviating from the specified dosage and administration of a medicine can lead to serious harm to health. Always read the product instructions carefully before use and follow the dosage and administration. Even when a medicine is used correctly according to the dosage and administration, side effects may occur. If you notice anything unusual, stop use immediately and consult a doctor or pharmacist.

About the Sale of Medicines

●Precautions for Use
■■Things You Must Not Do■■ (If not observed, current symptoms may worsen or side effects/accidents may become more likely to occur)
1. The following persons must not take this medicine.
(1) Persons who have had allergic symptoms caused by this medicine or its ingredients
(2) Persons who have had asthma caused by taking this medicine or other cold medicines or antipyretic analgesics
(3) Children under 15 years
(4) Pregnant women within 12 weeks of their expected delivery date
2. While taking this medicine, do not use any of the following medicines.
Other cold medicines, antipyretic analgesics, sedatives, antitussive and expectorants, oral medicines containing antihistamines, etc. (oral medicines for rhinitis, motion sickness medicines, allergy medicines, etc.), oral medicines containing tranexamic acid
3. Do not drive a vehicle or operate machinery after taking this medicine.
(Drowsiness, etc. may occur)
4. Persons who are breastfeeding should not take this medicine, or if taking this medicine, should avoid breastfeeding.
5. Do not drink alcohol before or after taking this medicine.
6. Do not take for more than 5 days.
■■Things To Consult On■■
1. The following persons should consult a doctor, pharmacist, or registered salesclerk before taking this medicine.
(1) Persons receiving treatment from a doctor or dentist
(2) Persons who are pregnant or who think they may be pregnant
(3) Elderly persons
(4) Persons who have had allergic symptoms caused by medicines, etc.
(5) Persons with the following symptoms
High fever, difficulty urinating
(6) Persons who have received the following diagnoses: thyroid dysfunction, diabetes, heart disease, high blood pressure, liver disease, kidney disease, glaucoma, systemic lupus erythematosus, mixed connective tissue disease; persons with blood clots (cerebral thrombosis, myocardial infarction, thrombophlebitis, etc.), persons at risk of developing thrombosis, respiratory dysfunction, obstructive sleep apnea syndrome, obesity
(7) Persons who have had the following diseases: gastric or duodenal ulcer, ulcerative colitis, Crohn's disease
2. If any of the following symptoms appear after taking this medicine, they may be side effects. Stop taking it immediately and consult a doctor, pharmacist, or registered salesclerk, bringing this document with you.

Relevant Area – Symptoms
Skin – Rash/redness, itching, bruising
Digestive system – Nausea/vomiting, loss of appetite, stomach discomfort, stomach pain, mouth ulcers, heartburn, heavy stomach, gastrointestinal bleeding, abdominal pain, diarrhea, bloody stools
Psychiatric/nervous system – Dizziness, excitement, convulsions
Circulatory system – Palpitations
Respiratory system – Shortness of breath
Urinary system – Difficulty urinating
Other – Blurred vision, ringing in the ears, swelling, nosebleeds, bleeding gums, bleeding that is difficult to stop, bleeding, back pain, excessive drop in body temperature, fatigue

The following serious symptoms may occur rarely.
In such cases, see a doctor immediately.

Symptom Name – Symptoms
Shock (anaphylaxis) – Immediately after taking the medicine, itching of the skin, hives, hoarseness, sneezing, itchy throat, difficulty breathing, palpitations, clouding of consciousness, etc. appear.

Oculomucocutaneous syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis – High fever, red eyes, eye discharge, sores on the lips, sore throat, widespread rash/redness of the skin, etc. persist or rapidly worsen.

Liver dysfunction – Fever, itching, rash, jaundice (yellowing of the skin or the whites of the eyes), brown urine, general fatigue, loss of appetite, etc. appear.

Kidney damage – Fever, rash, decreased urine output, swelling of the whole body, general fatigue, joint pain (aching joints), diarrhea, etc. appear.

Aseptic meningitis – Severe headache accompanied by stiffness of the neck, fever, nausea/vomiting, etc. appear. (Such symptoms have been reported especially often in persons receiving treatment for systemic lupus erythematosus or mixed connective tissue disease)

Myocardial infarction – Squeezing chest pain, difficulty breathing, cold sweats.

Cerebrovascular disorder – Decreased or lost consciousness, difficulty moving the arm and leg on one side, headache, vomiting, dizziness, difficulty speaking, difficulty getting words out, etc. appear suddenly.

Interstitial pneumonia – Shortness of breath or difficulty breathing when climbing stairs or exerting yourself slightly, dry cough, fever, etc. appear suddenly or persist.

Asthma – Wheezing or whistling sounds when breathing, difficulty breathing, etc. appear.

Aplastic anemia – Bruises, nosebleeds, bleeding from the gums, fever, pale-looking skin and mucous membranes, fatigue, palpitations, shortness of breath, feeling unwell and light-headed, blood in the urine, etc. appear.

Agranulocytosis – Sudden high fever, chills, sore throat, etc. appear.

Respiratory depression – Shortness of breath, difficulty breathing, etc. appear.

3. The following symptoms may appear after taking this medicine. If they persist or worsen, stop taking it and consult a doctor, pharmacist, or registered salesclerk, bringing this document with you.
Constipation, dry mouth, drowsiness

4. If symptoms do not improve after taking 5 to 6 doses, stop taking it and consult a doctor, pharmacist, or registered salesclerk, bringing this document with you. (Especially if fever continues for 3 days or more, or fever recurs)



●Indications
Relief of the various symptoms of a cold (sore throat, fever, chills, headache, runny nose, nasal congestion, sneezing, cough, phlegm, joint pain, muscle pain)



●Dosage and Administration
Take the following dose with water or hot water.
Age – Single dose – Times per day
Adults (15 years and older) – 2 tablets – 3 times; take preferably within 30 minutes after a meal.
Under 15 years – Do not take.

<Precautions related to dosage and administration>
(1) Strictly follow the dosage and administration.
(2) How to remove the tablets:
Press the raised part of the PTP sheet containing the tablet firmly with your fingertip to break the aluminum foil on the back, take out the tablet, and take it. (Accidentally swallowing the sheet as it is may lead to unexpected accidents, such as it piercing the mucous membrane of the esophagus)



●Ingredients and Amounts
This medicine is a white film-coated tablet, and 6 tablets contain the following ingredients.
Ingredient – Amount – Action
Tranexamic acid – 750 mg
– Suppresses [plasmin], the source of inflammation, and relieves swelling and pain in the throat.

Ibuprofen – 450 mg
– Acts on [prostaglandins], the source of inflammation and pain, suppressing sore throat, etc. and lowering fever.

Clemastine fumarate (1 mg as clemastine) – 1.34 mg
– Continuously suppresses allergic symptoms (runny nose, sneezing, etc.).

Bromhexine hydrochloride – 12 mg
– Makes it easier to cough up phlegm, one of the causes of coughing.

dl-Methylephedrine hydrochloride – 60 mg
– Dilates the bronchi and calms coughing.

Dihydrocodeine phosphate – 24 mg
– Acts on the cough center and calms coughing.

Thiamine nitrate (vitamin B1 nitrate) – 25 mg
– Promotes recovery of physical strength depleted by a cold.

Riboflavin (vitamin B2) – 12 mg
– Keeps the mucous membranes of the throat, nose, etc. healthy.

Additives: trehalose, cellulose, macrogol, croscarmellose sodium, polyvinyl alcohol (partially hydrolyzed), light anhydrous silicic acid, hydrogenated oil, magnesium stearate, hypromellose, titanium oxide, carnauba wax

<Precautions related to ingredients and amounts> The riboflavin (vitamin B2) contained in this medicine may turn your urine yellow.



●Precautions for Storage and Handling
(1) Store in a cool place with low humidity, away from direct sunlight.
(2) Store out of the reach of children.
(3) Do not transfer to another container. (This may cause misuse or change the quality)
(4) Do not use the product after the expiration date shown.

[Other information in the package insert] What causes a cold?
A cold is an "acute inflammatory disease of the upper respiratory tract," such as the "throat" and "nose."
Viruses, etc. enter the body through the throat, nose, etc. and trigger an excessive inflammatory response.
This inflammatory response causes respiratory symptoms such as sore throat, runny nose, cough, and phlegm, as well as fever and other symptoms.
The key to relieving cold symptoms is first to control and calm the inflammation.
It is also important to take vitamins and get plenty of sleep when you have a cold.



●Contact Information
For inquiries about this product, please contact the store where you purchased it or the following.
Daiichi Sankyo Healthcare Co., Ltd. Customer Consultation Office
〒103-8234 東京都中央区日本橋3-14-10
Tel. 0120-337-336
Hours: 9:00 to 17:00 (excluding Saturdays, Sundays, and public holidays)

Distributor
Daiichi Sankyo Healthcare Co., Ltd.
東京都中央区日本橋3-14-10

Manufacturer and Distributor
Shiga Pharmaceutical Co., Ltd.
滋賀県甲賀市甲賀町滝879番地